A PHP Error was encountered

Severity: Warning

Message: Creating default object from empty value

Filename: models/publicacao_item.php

Line Number: 20

Remarks on Antagonism » Isaúde
  Pesquisar Publicações Científicas  
  Especialidade: carregando especialidades...  Carregando...
Nome da revista:   Volume:   Número:
American journal of epidemiology
2011-05-03 21:37:44

Remarks on Antagonism

Descrição: Different forms of antagonism are classified in terms of response types and are related to the sufficient-cause framework. These forms of antagonism include "synergy under recoding of an exposure," "synergism under recoding of the outcome," and so-called "competing response types," with synergism itself conceived of as causal co-action within the sufficient-cause framework. In this paper, the authors show that subadditivity necessarily implies at least one of these 3 forms of antagonism. Empirical conditions for specific forms of antagonism are given for settings in which monotonicity assumptions are and are not considered plausible. The implications of subadditivity and superadditivity for causal co-action for either an outcome or its absence are characterized under various assumptions about monotonicity. A simple computational procedure is described for assessing whether any specific form of causal co-action can be detected for either an outcome or its absence for both cohort and case-control data. The results in this paper are illustrated by application to examples drawn from the existing literature on gene-gene and gene-environment interactions.

Identificador: i
Editorial: Oxford University Press
Número: 10
Volume: 173
Página: 1140 a 1147
Autor: VanderWeele, T. J., Knol, M. J.

Mais informações

  • Twitter iSaúde
Jornal Informe Saúde

Indique o portal
Fechar [X]
  • Você está indicando a notícia: http://www.isaude.net
  • Para que seu amigo(a) receba esta indicação preencha os dados abaixo:

RSS notícias do portal  iSaúde.net
Receba o newsletter do portal  iSaúde.net
Indique o portal iSaúde.net
Notícias do  iSaúde.net em seu blog ou site.
Receba notícias com assunto de seu interesse.
© 2000-2011 www.isaude.net Todos os direitos reservados.