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Alzheimer Disease and Associated Disorders
2019-04-01 05:00:00

Olfactory Impairment and Hippocampal Volume in a Chinese MCI Clinical Sample

Descrição: Purpose: The aim of this study was to evaluate the relationship between olfactory function and hippocampal volume in patients with mild cognitive impairment (MCI). Methods: We enrolled a total of 31 MCI patients and 9 normal control subjects. All participants underwent 3.0-T-magnetic resonance imaging scanning. The scan results were processed using GE ADW4.6 processing software and V0xar 3D workstation to acquire the hippocampal volume. The University of Pennsylvania Smell Identification Test (UPSIT) was used to evaluate the olfactory function of MCI patients. The correlations of UPSIT score with hippocampal volume and hippocampal head volume were evaluated by Pearson correlation coefficient analysis. Results: MCI patients had significantly smaller left (2.78?0.50 vs. 3.19?0.31-cm3) and right (2.97?0.42 vs. 3.31?0.25-cm3) hippocampal volumes compared with normal controls (P

Seção: Original Articles
Volume: 0
Autor: Han, Jee-young; Besser, Lilah M.; Xiong, Chengjie; Kukull, Walter A.; Morris, John C.


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