A PHP Error was encountered

Severity: Warning

Message: Creating default object from empty value

Filename: models/publicacao_item.php

Line Number: 20

Alzheimer-s Environmental and Genetic Risk Scores are Differentially... » Isaúde
  Pesquisar Publicações Científicas  
  Especialidade: carregando especialidades...  Carregando...
Nome da revista:   Volume:   Número:
Alzheimer Disease and Associated Disorders
2019-04-01 05:00:00

Alzheimer-s Environmental and Genetic Risk Scores are Differentially Associated With General Cognitive Ability and Dementia Severity

Descrição: Purpose: We investigated the association of the Australian National University Alzheimer-s Disease Risk Index (ANU-ADRI) and an Alzheimer disease (AD) genetic risk score (GRS) with cognitive performance. Methods: The ANU-ADRI (composed of 12 risk factors for AD) and GRS (composed of 25 AD risk loci) were computed in 1061 community-dwelling older adults. Participants were assessed on 11 cognitive tests and activities of daily living. Structural equation modeling was used to evaluate the association of the ANU-ADRI and GRS with: (1) general cognitive ability (g), (2) dementia-related variance in cognitive performance (-), and (3) verbal ability (VA), episodic memory (EM), executive function (EF), and processing speed (PS). Results: A worse ANU-ADRI score was associated with poorer performance in -g- [- (SE)=-0.40 (0.02), P

Seção: Original Articles
Volume: 0
Autor: Han, Jee-young; Besser, Lilah M.; Xiong, Chengjie; Kukull, Walter A.; Morris, John C.


Mais informações

  • Twitter iSaúde
publicidade
Jornal Informe Saúde

Indique o portal
Fechar [X]
  • Você está indicando a notícia: http://www.isaude.net
  • Para que seu amigo(a) receba esta indicação preencha os dados abaixo:

RSS notícias do portal  iSaúde.net
Receba o newsletter do portal  iSaúde.net
Indique o portal iSaúde.net
Notícias do  iSaúde.net em seu blog ou site.
Receba notícias com assunto de seu interesse.
© 2000-2011 www.isaude.net Todos os direitos reservados.