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Subjective Cognitive Impairment and the Broad Autism Phenotype » Isaúde
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Alzheimer Disease and Associated Disorders
2018-10-01 05:00:00

Subjective Cognitive Impairment and the Broad Autism Phenotype

Descrição: Introduction: Roughly 4% to 23% of the population embody stress prone personality and other traits characterizing a subclinical -broad autism phenotype- (BAP). Subjective cognitive impairment (SCI) among healthy elderly is associated with psychological distress leading us to predict BAP would be associated with SCI. Methods: The Autism Spectrum Quotient, a self-administered 50 item questionnaire, was completed by 419 consecutive members of the Arizona APOE Cohort who underwent neuropsychological testing every 2 years. SCI was assessed with self and informant versions of the Multidimensional Assessment of Neurodegenerative Symptoms (MANS) Questionnaire. Results: A total of 45 individuals scored in the BAP range, designated BAP+, and the rest were BAP-. At entry, both Multidimensional Assessment of Neurodegenerative Symptoms Questionnaire Self and Informant scores were higher in the BAP+ group (P

Seção: Original Articles
Volume: 0
Autor: Nguyen, Madeline T.; Mattek, Nora; Woltjer, Randy; Howieson, Diane; Silbert, Lisa; Hofer, Scott; Kaye, Jeffrey; Dodge, Hiroko; Erten-Lyons, Deniz


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