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Dementia Prevalence in Greece: The Hellenic Longitudinal... » Isaúde
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Alzheimer Disease and Associated Disorders
2018-07-01 05:00:00

Dementia Prevalence in Greece: The Hellenic Longitudinal Investigation of Aging and Diet (HELIAD)

Descrição: Introduction: Study of the epidemiology of dementia to gain insight into putative predisposing and prophylactic factors is the first step toward establishing effective preventive and therapeutic strategies for this ever-growing public health problem. Relevant data in Greece are scattered and outdated. Methods: We investigated dementia prevalence as part of a population-representative epidemiological study [Hellenic Longitudinal Investigation of Aging and Diet (HELIAD)] in 2 Greek regions. Results: Our sample comprised 1792 adults 65 years of age or older, who received a full neurological and neuropsychological evaluation that led to a consensus diagnosis. The overall prevalence of dementia was 5.0%, with 75.3% of the cases attributed to Alzheimer disease. Dementia odds were 15.8% higher for every year of advancing age and 9.4% lower for every additional year of education. Carrying at least 1 APOE--4 allele doubled the risk of dementia, whereas sex did not exert a statistically significant effect. Conclusions: Our results are consistent with previous research in Southern European countries; dementia prevalence in Greece is in the lower range of what has been reported globally.

Seção: Original Articles
Volume: 0
Autor: Grossberg, George T.; Alva, Gustavo; Hendrix, Suzanne; Ellison, Noel; Kane, Mary C.; Edwards, John


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