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Impact of Subcortical Hyperintensities on Dual-tasking in Alzheimer... » Isaúde
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Alzheimer Disease and Associated Disorders
2011-12-31 21:00:00

Impact of Subcortical Hyperintensities on Dual-tasking in Alzheimer Disease and Aging

Descrição: Subcortical hyperintensities (SHs) on brain magnetic resonance imaging are associated with cognitive and gait impairment in elderly but their impact on dual-tasking (performing cognitive tasks while walking) in patients with Alzheimer disease (AD) is unknown. This study explored the costs of dual-tasking in relation to SH severity in AD and normal controls (NCs). Cadence while walking on a treadmill, and speed-accuracy-tradeoff (SAT), on 3 working memory tasks, were measured during single-task and dual-task conditions. Dual-task costs (DTC) on SAT, cadence, and overall DTC were measured for each of these tasks. On visual rating of SH severity, AD and NC groups were subdivided into high-SH and low-SH subgroups. Compared with the NC, the AD group performed poorly on all working memory tasks across both conditions, decreased cadence on dual-tasking, and showed a decrement in overall DTC (all P

Seção: Original Articles
Volume: 0
Autor: Lauterbach, Edward C.


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