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The Efficacy of Nonpharmacological Treatment for Dementia-related Apathy » Isaúde
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Alzheimer Disease and Associated Disorders
2011-07-01 00:00:00

The Efficacy of Nonpharmacological Treatment for Dementia-related Apathy

Descrição: Objective: To determine the usefulness of a formal, structured, nonpharmacological treatment for apathetic dementia patients.Patients and Methods: A controlled, cross-over, randomized, simple-blind, multicentre clinical trial. A total of 146 institutionalized or day care dementia patients with a stage 1 or 2 Clinical Dementia Rating, with no significant motor or sensory problems, or with rapidly evolving dementia and in a clinically stable state were recruited. A cognitive mini examination, and functional, depression, and potential toxicity scales, Neuropsychiatric Inventory Questionnaire (NPI-Q), and Dementia Apathy Interview and Rating (DAIR) scales were applied at baseline. Patients were randomized to initial intervention (music and art therapy and psychomotor activity) or initial control (free activities in the day room) and changed over at 4 weeks. NPI-Q and DAIR scales were administered at the end of weeks 4 and 8.Results: A significant difference between intervention and control periods, as measured using the DAIR scale, was observed, with a difference of 0.21 (95% confidence interval: 0.07-0.34, P

Seção: Original Articles
Volume: 0
Autor: Chin, Alexander L.; Negash, Selamawit; Hamilton, Roy


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