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Comparative study of fibrosis induced by Marlex?, Parietex... » Isaúde
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Acta Cirurgica Brasileira
0000-00-00 00:00:00

Comparative study of fibrosis induced by Marlex?, Parietex Composite?, Vicryl? and Ultrapro? meshes1

Descrição: Abstract Purpose: To evaluate the fibrosis induced by four different meshes: Marlex?, Parietex Composite?, Vicryl? and Ultrapro?. Methods: Histological cutouts of abdominal wall were analyzed with polarized light 28 days after the meshes implants and colorized by picrosirius to identify the intensity of collagen types I and III, and their maturation index. Results: When the four groups were compared, the total collagen area analyzed was bigger in groups A and D, with no difference between them. The collagen type I density was bigger in group A, with an average of 9.62 ? 1.0, and smaller in group C, with an average of 3.86 ? 0.59. The collagen type III density was similar in groups A, B and C, and bigger in group D. The collagen maturation index was different in each of the four groups, bigger in group A with 0.87, group B with 0.66, group D with 0.57 and group C with 0.33 (p = 0.0000). Conclusion: The most prominent fibrosis promotion in the given meshes was found on Marlex? (polypropylene mesh) and the Parietex Composite? (non-biodegradable polyester); the collagen maturation index was higher in the Marlex? mesh, followed by Ultrapro?, Parietex Composite? and Vicryl? meshes.

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