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Dietary rice bran promotes resistance to Salmonella enterica serovar... » Isaúde
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BMC microbiology [electronic resource]
2012-05-14 09:32:47

Dietary rice bran promotes resistance to Salmonella enterica serovar Typhimurium colonization in mice

Descrição: Background:Dietary rice bran consists of many bioactive components with disease fighting properties; including the capacity to modulate the gut microbiota. Studies point to the important roles of the gut microbiota and the mucosal epithelium in the establishment of protection against enteric pathogens, such as Salmonella. The ability of rice bran to reduce the susceptibility of mice to a Salmonella infection has not been previously investigated. Therefore, we hypothesize that the incorporation of rice bran into the diet will inhibit the colonization of Salmonella in mice through the induction of protective mucosal responses.Results:Mice were fed diets containing 0%, 10% and 20% rice bran for one week prior to being orally infected with Salmonella enterica serovar Typhimurium. We found that mice consuming the 10 and 20% rice bran diets exhibited a reduction in Salmonella fecal shedding for up to nine days post-infection as compared to control diet fed animals (p

Identificador: doi:10.1186/1471-2180-12-71
Volume: 0
Página: 7 a


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