A PHP Error was encountered

Severity: Warning

Message: Creating default object from empty value

Filename: models/publicacao_item.php

Line Number: 20

Collapsing Glomerulopathy as a Complication of Type I... » Isaúde
  Search scientific publications  
  Especialidade: carregando especialidades...  Loading...
Name of the journal:   Volume:   Number:
American Journal of Kidney Diseases
2021-04-16 00:00:00

Collapsing Glomerulopathy as a Complication of Type I Interferon-Mediated Glomerulopathy in a Patient With RNASEH2B-Related Aicardi-Gouti?res Syndrome

Description: Aicardi-Gouti?res syndrome (AGS) is a well-characterised monogenic type I interferonopathy presenting with prominent neurological manifestations. Among extra-neurological features, renal involvement has only been described in one IFIH1-mutated patient who developed membranous nephropathy. The pathogenic role of augmented interferon signalling in tissues other than the central nervous system remains to be elucidated. We report a case of collapsing glomerulopathy (CG) in a 15-year-old girl affected by AGS with RNASEH2B mutation (p.Ala177Thr), which led to end-stage renal disease.

Identifier: 10.1053/j.ajkd.2021.02.330
Section: Case Reports
Volume: 0
Author: Paride Fenaroli, Giovanni M. Rossi, Maria Lucia Angelotti, Giulia Antonelli, Stefano Volpi, Alice Grossi, Marco Delsante, Lorenzo Lodi, Samuela Landini, Paola Romagnani, Augusto Vaglio

More info

  • Twitter iSaúde
Informe Saúde printed version

Recommend the portal
Close [X]
  • You are recommending this story: http://www.isaude.net
  • Fill in the following form to send your recommendation to your friend:

RSS news from the portal  iSaúde.net
Get the newsletter of the portal  iSaúde.net
Recommend the portal iSaúde.net
News from  iSaúde.net in your blog or website.
Get news on the subject of your interest.
© 2000-2011 www.isaude.net Todos os direitos reservados.