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APOL1, Black Race, and Kidney Disease: Turning Attention to... » Isaúde
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American Journal of Kidney Diseases
2021-01-21 00:00:00

APOL1, Black Race, and Kidney Disease: Turning Attention to Structural Racism

Description: The incidence of end-stage kidney disease (ESKD) is nearly three times higher in Black relative to White Americans.1 A significant body of biomedical literature links this racial inequity to polymorphic variation in the gene encoding apolipoprotein L1 (APOL1). In fact, in a PubMed search of -APOL1- and -kidney disease,- 86 percent of results feature abstracts mentioning African ancestry or African American, Black, or non-White race. Multiple recent articles state that APOL1 genetic variants are found -exclusively- in people, or chromosomes, of -African- origin.

Identifier: 10.1053/j.ajkd.2020.11.029
Section: Editorials
Volume: 0
Author: Jessica P. Cerde?a, Jennifer Tsai, Vanessa Grubbs


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