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COVID-19-Related Collapsing Glomerulopathy in a Kidney Transplant... » Isaúde
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American Journal of Kidney Diseases
2020-07-11 00:00:00

COVID-19-Related Collapsing Glomerulopathy in a Kidney Transplant Recipient

Description: We report a case of a kidney transplant recipient who presented with acute kidney injury and nephrotic-range proteinuria in a context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Kidney biopsy revealed collapsing glomerulopathy. Droplet-based digital PCR did not detect the presence of SARS-CoV-2 RNA in the biopsy fragment, and the virus was barely detectable in the plasma at the time of the biopsy. SARS-CoV-2 RNAemia peaked several days later, followed by a seroconversion despite the absence of circulating CD19-positive lymphocytes at admission due to rituximab-based treatment of antibody-mediated rejection 3 months earlier.

Identifier: 10.1053/j.ajkd.2020.06.009
Section: Case Reports
Volume: 0
Author: H?l?ne Lazareth, H?l?ne P?r?, Yannick Binois, Melchior Chabannes, Juliet Schurder, Thomas Bruneau, Alexandre Karras, Eric Thervet, Marion Rabant, David Veyer, Nicolas Pallet


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