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Use of Gadolinium-Based Contrast Agents in Kidney Disease Patients:... » Isaúde
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American Journal of Kidney Diseases
2020-04-10 00:00:00

Use of Gadolinium-Based Contrast Agents in Kidney Disease Patients: Time for Change

Description: Gadolinium-based contrast agents (GBCAs) are molecularly heterogeneous with various chelates holding the paramagnetic element gadolinium. Chelates are either linear or macrocyclic, ionic or nonionic (Table?11-5). Historically, nephrologists did not differentiate among these agents. About 2 decades ago, the novel entity nephrogenic systemic fibrosis (NSF) was first reported by Cowper et?al6 in patients with chronic kidney disease (CKD) stage 5 treated by dialysis (CKD5D). Several years later, its association with a GBCA was first noted.

Identifier: 10.1053/j.ajkd.2020.03.011
Section: In the Literature
Volume: 0
Author: Ali K. Abu-Alfa

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