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D?j? Vu But New: Using T Cells to Deplete B Cells to Treat Lupus » Isaúde
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American Journal of Kidney Diseases
2019-05-30 00:00:00

D?j? Vu But New: Using T Cells to Deplete B Cells to Treat Lupus

Description: Systemic lupus erythematosus is a severe, incurable autoimmune disease with an incidence of 5 per 100,000 people in the United States1 and a global burden of disease that likely exceeds 5 million people.2 Lupus nephritis is one of the most dreaded manifestations of lupus, affecting both quality of life and life expectancy. Kidney damage and end-stage kidney disease increase the risk for mortality 3.6- and 9.2-fold, respectively.3 Standard treatment for lupus nephritis entails nonspecific immunosuppression that carries the risk for serious side effects, highlighting the need for novel, less toxic therapies.

Identifier: 10.1053/j.ajkd.2019.04.009
Section: In the Literature
Volume: 0
Page: 708 a 710
Author: Rebecca E. Sadun, Mary H. Foster


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