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publicado em 30/05/2013 às 10h00:00
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Babies born by cesarean are 84% more likely to be overweight

Results suggest that the current epidemic of obesity could be driven in part by the increase in the number of caesarean sections

 
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Cesariana está associada ao aumento de massa corporal na infância e adolescência
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Cesariana está associada ao aumento de massa corporal na infância e adolescência

T o assess associations of caesarean section with body mass from birth through adolescence.

Longitudinal birth cohort study, following subjects up to 15 years of age.

Children born in 1991 1992 in Avon, UK who participated in the Avon Longitudinal Study of Parents and Children (ALSPAC) (n=10219).

Primary outcome: standardized measures of body mass (weight-for length z-scores at 6 weeks, 10 and 20 months; and body mass index (BMI) z-scores at 38 months, 7, 9, 11 and 15 years). Secondary outcome: categorical overweight or obese (BMI 85th percentile) for age and gender, at 38 months, 7, 9, 11 and 15 years.

Of the 10219 children, 926 (9.06%) were delivered by caesarean section. Those born by caesarean had lower-birth weights than those born vaginally (-46.1g, 95% confidence interval(CI): 14.6 77.6g; P=0.004). In mixed multivariable models adjusting for birth weight, gender, parental body mass, family sociodemographics, gestational factors and infant feeding patterns, caesarean delivery was consistently associated with increased adiposity, starting at 6 weeks (+0.11s.d. units, 95% CI: 0.03 0.18; P=0.005), through age 15 (BMI z-score increment+0.10s.d. units, 95% CI: 0.001 0.198; P=0.042). By age 11 caesarean-delivered children had 1.83 times the odds of overweight or obesity (95% CI: 1.24 2.70; P=0.002). When the sample was stratified by maternal pre-pregnancy weight, the association among children born of overweight/obese mothers was strong and long-lasting. In contrast, evidence of an association among children born of normal-weight mothers was weak.

Caesarean delivery is associated with increased body mass in childhood and adolescence. Research is needed to further characterize the association in children of normal weight women. Additional work is also needed to understand the mechanism underlying the association, which may involve relatively enduring changes in the intestinal microbiome.

Source: Isaude.net
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Cesarean section    childbirth    obesity    obesity epidemic    New York University School of Medicine    Jan Blustein   
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