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publicado em 30/01/2013 às 09h41:00
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French announce early tests Aids vaccine in humans

The patients will be vaccinated three times, with one month interval between doses, and should discontinue treatment with the cocktail

 
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After the success of toxicity tests, scientists announced the initiation of clinical trials of AIDS vaccine, in Marseille, southern France.

Forty-eight volunteer patients will receive three different doses of vaccine. Preliminary results are expected in a few months, "says Erwann Loret responsible for the research.

The patients will be vaccinated three times, with one month interval between each dose. After this period, they should discontinue treatment with the cocktail.

"If after these two months, the rate of virus in the blood is undetectable, so the study has met the criteria established by UNAIDS. With these results we can move on to another phase of research with the participation of a group of 80 volunteers, half taking the vaccine and half a placebo, said Loret.

For 10 years researching the vaccine, Erwann Loret is a member of the National Center for Scientific Research in France (CNRS) and director of the Institute of Structural Biology and Microbiology Timone. He was responsible for creating the molecule anti-Aids, an active product that targets the protein TAT. This protein prevents the immune system of AIDS patients to "cleanse" the body of infected cells and is the basis of untested vaccine now.

In 2001, a vaccine developed in Marseille was injected seven monkeys. A year later, the monkeys were infected with SHIV, a hybrid virus between HIV and SIH (virus that affects monkeys). "After 56 days, the mice showed no more signs of the virus, confirming the effectiveness of the vaccine, which had already been successfully tested in rabbits," said Loret.

He completed stating that even if the tests are positive, it is not expected to end AIDS but replacing the current cocktail, which causes several side effects for a vaccine.

Source: Isaude.net
   Palavras-chave:   AIDS vaccine    AIDS    HIV    SHIV    SIH    Erwann Loret      
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