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publicado em 16/01/2013 às 16h21:00
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Brazilians develop pioneering drug to treat hypertension in pregnant women

Difficulty in treating pre-eclampsia may be overcome soon with new antihypertensive drug

 
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Researchers have developed antihypertensive medication for the duration of pregnancy Professor at the Institute of Biological Sciences, UFMG, Robson Augusto Souza dos Santos
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Researchers have developed antihypertensive medication for the duration of pregnancy
Professor at the Institute of Biological Sciences, UFMG, Robson Augusto Souza dos Santos

Preeclampsia, a disease specific to pregnancy, when it evolves to severe form, eclampsia, is responsible for about 40% of deaths of women from pregnancy and childbirth in Brazil. Despite the high incidence in the population, the causes of these diseases have not been well established and there are no drugs on the market targeted specifically to their treatment because traditional remedies may endanger fetal development.

But this difficulty can be overcome in the treatment soon because a novel antihypertensive drug for the period of pregnancy developed by a group of Brazilian researchers from the Federal University of Minas Gerais (UFMG) and Union Chemical Company has passed the first phase of testing clinicians.

We imagine the completion of all clinical trials in two years and a conservative forecast, the drug could be launched within five years. This period will depend on the part of regulatory bodies, said Dr. Robson Augusto Souza dos Santos, professor at the Institute of Biological Sciences (ICB) UFMG. Santos also coordinates the National Institute of Science and Technology in Nanobiofarmacêutica (INCT-Nanobiofar), headquartered at the same university.

The current drugs to control blood pressure act on the mechanism of vasoconstrictor renin-angiotensin system and are not endogenous, ie produced by the body itself, but molecules made in the laboratory. For this reason, they have side effects, explains the coordinator INCT-Nanobiofar. The drug that we are developing this problem does not provide for peptide itself be synthesized by biochemical means, but with the same composition as existing in the human body. According to Santos, the drug, when finalized, may also be used to treat hypertension general. Previous studies showed that the drug has reduced the blood pressure of hypertensive rats. The next step will be to test in humans, says

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Source: Isaude.net
   Palavras-chave:   Hypertension    Pregnancy    Pre-eclampsia    Eclampsia    Antihypertensive renin-angiotensin   
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hypertension    pregnancy    pre-eclampsia    eclampsia    antihypertensive renin-angiotensin   
Comments:
Comment
Gilma
posted on:
16/01/2013 19:44:52
Oh notícia boa, parabéns, só não demorem muito para colocar ao alcance das gestantes que necessitarem por favor, é urgente!
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