Science and Technology
publicado em 11/01/2013 às 19h41:00
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Fiocruz bet on nanotechnology to invest in new drugs

Goal is to treat diseases that afflict millions of people in the world today, such as schistosomiasis and AIDS

 
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Foto: Ministério da Saúde
Laboratories of the Institute of Drug Technology. Farmanguinhos is involved in research to produce drugs against schistosomiasis and AIDS
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Laboratories of the Institute of Drug Technology. Farmanguinhos is involved in research to produce drugs against schistosomiasis and AIDS

In order to treat diseases that afflict millions of people around the world: AIDS and schistosomiasis, the Institute of Drug Technology (Farmanguinhos / Fiocruz) bet on two studies involving the development of drugs with the use of nanotechnology. According to Flávio physical Plentz, ahead of the Micro and Nanotechnology Coordination of the Ministry of Science and Technology, everything would be possible with the manipulation of nanoparticles in the laboratory.

One of the surveys conducted in Farmanguinhos is about a new formulation for Praziquantel (PZQ), a drug indicated for the treatment of schistosomiasis. Popularly known as belly-the water, is a major neglected disease affects about 200 million people worldwide and 8 million in Brazil.

Protected a capsule microscopic PZQ unscathed through the acidic stomach and liver. In the bloodstream, where he encounters should act when a small molecule then kicks in and opens the capsule, releasing an accurate bombing against the army of parasites occupying the body of the patient. A sort of guided missile pharmacist.

The drug will be manufactured at the new plant nanopolímeros Coppe / UFRJ, opened in October. Result of an investment of $ 11 million, the Pilot Plant Polymer occupies an area of ​​740 m2 in the Engineering Laboratory of Polymerization Coppe. The installation is the first in the country able to produce micro-and nanoparticles with applications in the medical, pharmaceutical and biotech.

<b> HIV </ b>

Another research Farmanguinhos using nanotechnology is focused on the treatment of AIDS. This is the development of an antiretroviral. Despite still being in its infancy, the study has shown promising results.

While microrrobótica is still invisible in Brazil, with isolated initiatives and investments sprayed nanotechnology as a whole entered the radar of government. The Ministry of Science and Technology will increase by 20 times the budget for this field in 2013: £ 101 million. Additionally, graduated this year a committee of ten ministries to evaluate new incentive policies. The ministry is expected to announce later this month laboratories which receive federal funds within a program called SisNano. A counterpart: grantees must provide 15% of their time to external users such as businesses. To gain greater robustness, says physicist Plentz.

Source: Isaude.net
   Palavras-chave:   Nanotechnology    Schistosomiasis    AIDS    Fiocruz    Treatment    Praziquantel    PZQ    Farmanguinhos   
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