Science and Technology
publicado em 26/12/2012 às 15h44:00
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Award winning enables detection of diseases such as Parkinson's in its early stages, benefiting patients

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Degenerative diseases of the central nervous system has advances in early diagnosis, which will reflect in the quality of life of patients. Researchers Paulo Roberto Bueno, professor at the Institute of Chemistry Unesp (IQ), Campus de Araraquara, and Jason Davis, Department of Chemistry, University of Oxford, do work together on biomarkers and are responsible for innovation.

Professor IQ explains that the abundance of certain specific proteins may be an indicator of premature diseases like Parkinson's and Huntington Alzmeimer. Current methods for mapping proteins in search of indicators of disease involving specialized equipment and very expensive. These methods also involve complex analytical procedures.

In contrast, electrical detection methods have high sensitivity, are cheaper and can detect multiple proteins simultaneously. However, methodologies electroanalysis, though powerful, are facing problems of flexibility.

Bueno and Davis have developed technology that allows rapid quantification of biomarkers. This detection is flexible and easy to use. They demonstrated, in preliminary studies, the ability to detect markers associated with neurodegeneration in an early stage of disease. This capability is innovative and can profoundly affect the patient's quality of life and ability to treat diseases such as Parkinson's.

The work was awarded the project of scientific innovation: 'The sensitive multiplex detection of disease markers using immittance eletrochemical', in London, England and had five articles in scientific publications.

<i> information Unesp <i>

   Palavras-chave:   Biomarkers    Parkinson    Alzmeimer    Huntington    Early diagnosis    UNESP    Oxford   
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