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publicado em 26/11/2012 às 07h52:00
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New british study says that smoking may "rot" the brain

Cigarette affects learning, memory and reasoning. Hypertension and overweight also alter the brain, but to a lesser degree

 
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O cigarro apodrece o cerebro humano, afirmam pesquisadores
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O cigarro apodrece o cerebro humano, afirmam pesquisadores

The objective of the present study was to explore the association between cardiovascular risk and cognitive decline in adults aged 50 and over.

Participants were older adults who participated in the English Longitudinal Study of Ageing.

Outcome measures included standardised z-scores for global cognition, memory and executive functioning. Associations between cardiovascular risk factors and 10-year Framingham risk scores with cognitive outcomes at 4-year and 8-year follow-ups were estimated.

The mean age of participants (n = 8,780) at 2004 05 survey was 66.93 and 55% were females.

Participants in the highest quartile of Framingham stroke risk score (FSR) had lower global cognition (b = ?0.73,CI: ?1.37, ?0.10), memory (b = ?0.56, CI: ?0.99, ?0.12) and executive (b = ?0.37, CI: ?0.74, ?0.01) scores at 4-year follow-up compared with those in the lower quartile.

Systolic blood pressure ?160 mmHg at 1998 2001 survey was associated with lower global cognitive (b = ?1.26, CI: ?2.52, ?0.01) and specific memory (b = ?1.16, CI: ?1.94, ?0.37) scores at 8-year follow-up. Smoking was consistently associated with lower performance on all three cognitive outcomes.

The results showed that elevated cardiovascular risk may be associated with accelerated decline in cognitive functioning in the elderly. Future intervention studies may be better focused on overall risk rather than individual risk factor levels.

Source: KING'S COLLEGE LONDON
   Palavras-chave:   Smoking    Cigarette smoking    Hypertension    Obesity    Cognitive decline    King's College London    Alex Dregan   
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