General
publicado em 24/09/2012 às 13h09:00
   Dê o seu voto:

Molecule of the immune system affects hunger and regulates body weight

New insight into the role of interleukin-6 on weight loss can lead to new treatments for obesity, say researchers

 
font size
A-
A+
Foto: Jason Stitt/Depositphotos
Cientistas afirmam que entender como a gordura existente nos alimentos influencia na percepção do sabor pode auxiliar na criação de alimentos mais saudáveis e menos gordurosos, sem afetar o gosto
  « Previous
next »  
Cientistas afirmam que entender como a gordura existente nos alimentos influencia na percepção do sabor pode auxiliar na criação de alimentos mais saudáveis e menos gordurosos, sem afetar o gosto

Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have identified a molecule in the immune system that could affect hunger and satiety. The researchers hope that new treatments for obesity will benefit from this finding.

Interleukin-6 is a chemical messenger in our immune system that plays an important role in fighting off infection. However, recent research has, surprisingly, shown that it can also trigger weight loss. Researchers at Sahlgrenska Academy, University of Gothenburg, have been investigating and managed to identify the specific types of brain cells that are targeted by the interleukin-6 molecule.

The results show that the cells that are affected by interleukin-6 produce substances that not only affect our sense of hunger and fullness but also control the body' s ability to burn fat. " Interleukin-6 increases levels of substances in the brain that trigger weight loss, which could explain why high levels of this molecule lead to weight loss," says doctoral student Erik Schéle, who is presenting the results in his thesis.

It is known that our normally low levels of interleukin-6 in the brain increase dramatically during an infection, typically accompanied by reduced hunger and fatigue.

" Our previous findings would indicate that interleukin-6 can play a key role in regulating the metabolism of healthy individuals too," says Erik Schéle.

" This is clearly substantiated by our finding that mice which lack interleukin-6 get fat, and that the metabolism of rats injected with interleukin-6 directly into the brain increases."

Although it is not yet fully understood how interleukin-6 in the brain affects bodyweight, the researchers have concluded that anyone whose brain produces plenty of interleukin-6 could be protected against overweight. The thesis also shows that our gut bacteria indirectly affect the substances in the brain that regulate bodyweight.

" This is both surprising and new. It could in the long run lead to people fighting obesity by changing what they eat in line with how it affects the brain," says Erik Schéle.

Source: Isaude.net
   Palavras-chave:   Immune system    Hunger    Satiety    Overweight    University of Gothenburg    Erik Schele   
  • Share this pageShare this page
  • Share this pageCorrect
  • ShareShare
  • AlertAlert
Reduced link: 
  • You are recommending this story: Molecule of the immune system affects hunger and regulates body weight
  • Fill in the following form to send your recommendation to your friend:

  • You are suggesting a correction for this story: Molecule of the immune system affects hunger and regulates body weight


Receba notícias do iSaúde no seu e-mail de acordo com os assuntos de seu interesse.
Seu nome:
Seu email:
Desejo receber um alerta com estes assuntos:
Immune system    hunger    satiety    overweight    University of Gothenburg    Erik Schele   
Comments:
Comment
Leave your comment
Close
(Required fields are marked with an *)

(Your email address will never be published or shared.)

Enter the letters and numbers below and click in the button "send"

  • Twitter iSaúde
advertising
Informe Saúde printed version

Recommend the portal
Close [X]
  • You are recommending this story: http://www.isaude.net
  • Fill in the following form to send your recommendation to your friend:

RSS news from the portal  iSaúde.net
Get the newsletter of the portal  iSaúde.net
Recommend the portal iSaúde.net
News from  iSaúde.net in your blog or website.
Get news on the subject of your interest.
© 2000-2011 www.isaude.net Todos os direitos reservados.