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publicado em 16/09/2012 às 18h00:00
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Distinct types of fear traverse different paths in the brain

Brazilian study, highlighted in Nature, could lead to understanding of problems like panic disorder and post-traumatic stress

 
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Studies conducted by researchers from Brazil and the United States show that, unlike previously thought, distinct types of fear - fear of stimuli as painful, fear of natural predators and fear of aggressive members of the same species - are processed in neural circuits independent of each other, taking different paths in the brain. The experiments were highlighted on the cover of Nature Reviews Neuroscience September.

Besides distinguishing neural pathways processing of instinctive fears and different types of learned fears - the researchers also found that these mechanisms can also reproduce in humans. Thus, the studies may contribute to a better understanding of problems like panic disorder and post-traumatic stress.

One of the key points highlighted in the article was the discovery that, in rodents, the circuit related to the fear caused by the threat of a natural predator may be the same circuit activated in humans when they face threats to their lives, "the coordinator of Newton Canteras study. Surveys conducted in mice at the Institute of Biomedical Sciences (ICB), University of São Paulo (USP) were based on the induction of stimuli in animals instinctive fears, which are characterized as a survival mechanism, and learned fears, that are cultural and acquired lifelong.

According Canteras, when the subject began to be studied by his group, around 1995, prevailed in the scientific community organization of a unitary theory of fear responses in the nervous system.

He said the findings were considered important because a number of human diseases derived from fear - like anxiety, panic disorder and post-traumatic stress. "This finding may help us understand situations such as post-traumatic stress, said.

<i> information Fapesp </ i>

Leia mais detalhes da pesquisa em português.

Veja o artigo The many paths to fear, que pode ser lido por assinantes da Nature Reviews Neuroscience.

Source: Isaude.net
   Palavras-chave:   Fear    Brain    Neuroscience    Nature Reviews Neuroscience    USP    Universidade de São Paulo   
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