Science and Technology
publicado em 08/09/2012 às 09h00:00
   Dê o seu voto:

Researchers using compound glass to regenerate injured bone

Brazilian invention uses highly bioactive material able to interact and promote regeneration of bone tissue

 
font size
A-
A+

Some pieces of information on this page may have been automatically translated. Makernews is not responsible for the irregularities resulting from these translations. When in doubt,      consult the original text.



Foto: Universidade Federal de São Carlos
Material is highly bioactive and has the ability to interact with bone tissue regeneration providing
  « Previous
next »  
Material is highly bioactive and has the ability to interact with bone tissue regeneration providing

Studies conducted at Federal University of São Carlos (UFSCar) are proposing new techniques and products for the development of artificial bone grafts. Researchers from the Laboratory of Vitreous Materials (LaMaV) Institution recently patented an invention that uses Biosilicato, a material obtained from a crystallization process of glass that is highly bioactive and has the ability to interact with bone tissue and promote their regeneration.

The size of the importance of the invention can be measured by researchers relevance treatment of bone lesions, since bone tissue is considered, after the blood, the second most frequently transplanted tissue. Furthermore, the researchers point out that the lab's aging population and the increase of orthopedic surgeries using bone grafts have expanded at a rapid rate of growth, this type of clinical need and market for treatments based biomaterials.

Currently, the most used by physicians in the treatment of bone fractures is the autograft, performed with material from the patient himself. However, the small amount of material available, the risk of infection and need for additional surgeries, among other complications render this therapy unsatisfactory.

According to the researcher's LaMaV Ana Rodrigues, the use of autograft, which depends on the use of patient's own bone, is very limited, because it requires the definition of a location to extract the bone that does not compromise the health of the person. It is a limiting factor and that by making the removal of material, ends up creating a lesion in another area, says the researcher.

<b> Challenges </ b>

In the treatment of bone fractures from the new invention, the challenge has been to develop a type of material that is highly porous while also having mechanical properties closest to bone with which it will interact. According to the researchers, the proposal would use a graft from scaffolds based Biosilicato has the advantage of material designed to have a porous structure that allows the growth of bone tissue inside and a subsequent resorption of bioactive material in the body of the patient. The Scaffolds are alloplastic grafts, or artificial. In practice are porous structures that serve as templates for the growth of bone tissue. There are several materials that can be used in the synthesis of scaffolds, among them, some types of glass.

The aging population and the increase in orthopedic surgery using bone grafts have expanded at a rapid rate of growth, this type of clinical need and market for treatments based biomaterials.

Partnerships with LaMaV kept for tests with scaffolds involve researchers from the departments of Physiotherapy and Pathology and Morphology UFSCar and the Department of Biosciences, Universidade Federal de São Paulo (Unifesp) and the Faculty of Dentistry of Ribeirão Preto, USP.

The next phase is the clinical test, which involves the application in humans. At this stage there are strict ethical protocols to be followed until it is proven the effectiveness or otherwise of the proposal. Researchers estimate that between 5 and 10 years the proposal may have advanced and be available as an option in the surgical treatment of bone fractures.

Story

The use of glasses as biomaterials was initially proposed in 1969 by Larry Hench, Professor Emeritus of Imperial College, London. His group has identified certain types of glasses, which later became known as bioactive, meaning that the interaction with the human body that respond biologically material forming a chemical bond between the living tissue and the material used.

The glass-ceramics and glassy materials are already commonly used in other applications. There are applications in cooking plates, plates support for telescope, lamp holders, among others. The application as a biomaterial, however, caught the attention of researchers LaMaV who first developed the Biosilicato, produced from a special heat treatment of the glass. The substance has been used successfully in clinical trials for the treatment of hypersensitive teeth, in powder form and incorporated in toothpaste. According to the researchers, it is as bioactive as Bioglass 45S5, glass developed by Hench, and has the highest bioactivity among all known materials.

Source: Isaude.net
   Palavras-chave:   Bone    Glass    Regeneration    Biosilicato    Federal University of São Carlos    UFSCar    Vitreous Materials Laboratory    LaMaV   
  • Share this pageShare this page
  • Share this pageCorrect
  • ShareShare
  • AlertAlert
Reduced link: 
  • You are recommending this story: Researchers using compound glass to regenerate injured bone
  • Fill in the following form to send your recommendation to your friend:

  • You are suggesting a correction for this story: Researchers using compound glass to regenerate injured bone


Receba notícias do iSaúde no seu e-mail de acordo com os assuntos de seu interesse.
Seu nome:
Seu email:
Desejo receber um alerta com estes assuntos:
bone    glass    regeneration    Biosilicato    Federal University of São Carlos    UFSCar    Vitreous Materials Laboratory    LaMaV   
Comments:
Comment
Leave your comment
Close
(Required fields are marked with an *)

(Your email address will never be published or shared.)

Enter the letters and numbers below and click in the button "send"

  • Twitter iSaúde
advertising
Informe Saúde printed version

Recommend the portal
Close [X]
  • You are recommending this story: http://www.isaude.net
  • Fill in the following form to send your recommendation to your friend:

RSS news from the portal  iSaúde.net
Get the newsletter of the portal  iSaúde.net
Recommend the portal iSaúde.net
News from  iSaúde.net in your blog or website.
Get news on the subject of your interest.
© 2000-2011 www.isaude.net Todos os direitos reservados.