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publicado em 27/08/2012 às 15h00:00
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Into research on tumor stem cells to treat bone cancer

Search launches a new line of study and will be the first held with tumor stem cells in the laboratory of the institute

 
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Foto: Ministério da Saúde
Technical INTO Laboratory of Cellular Therapy. Study aims to study tumor stem cells
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Technical INTO Laboratory of Cellular Therapy. Study aims to study tumor stem cells

The National Institute of Traumatology and Orthopedics Jamil Haddad (Into) began this month, a survey of stem cells in patients with osteosarcoma, malignant bone tumor that affects mainly children and young people between 10 and 20 years on stage growth. The research opens a new line of study and will be held the first stem cell Tumor Research Center at Orthopaedic Bioengineering and Cell Therapy Into the.

The study will consist in isolation and in vitro expansion of tumor stem cells in two stages: At the time of biopsy, performed for confirmation of the disease, and after treatment with chemotherapy. Researchers will identify the amount of cells present in these two phases and comparing them to verify the aggressiveness of the tumor and the degree of resistance to treatment. Also tests will be performed in sterile mice to cause disease and to monitor tumor development in vivo.

According to the head of the Research Division, Maria Eugenia Duarte, the amount of stem cells may be related to tumor aggressiveness, resistance to treatment and the spread of disease in the body. The result is that one may provide more important to treat the patient and will be able to identify if there was no response to treatment. From there, physicians can better plan treatment based on the individual characteristics of each tumor.

The expectation of Walter Meohas orthopedic surgeon specializing in the treatment of osteosarcoma is that the results can help to reduce the need for amputations. It is an unprecedented survey that will revolutionize the treatment. I am optimistic to make it work and we can preserve more children. It is a prospective study, starting with those who are now coming to do a biopsy to confirm the diagnosis. The doctor meets and in Into the National Cancer Institute (INCA) approximately 31 cases / year in patients with osteosarcoma who need cancer surgery.

Source: Isaude.net
   Palavras-chave:   Stem cells    Bone cancer    Osteosarcoma    Malignant tumor    Children   
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