publicado em 26/08/2012 às 09h00:00
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Study suggests distinct timetable for vaccination against H1N1 in the country

According Fiocruz researcher, change is due to cultural diversity, climate, topography and population habits

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Due to cultural, climatic, topographic and habits of the population, a study by the Fundação Oswaldo Cruz (Fiocruz) suggests a separate schedule of vaccination against swine flu (H1N1) for each site. Could be more effective if designed so regional, should also consider the narrow period between the determination of virus circulating in the world and annual production of the vaccine, says coordinator Programs and Projects Fiocruz Brasilia, Jose Cerbino. The finding is part of the thesis Pandemic Influenza in Brazil: epidemiology, treatment and prevention of Influenza A, defended by Cerbino.

He said the tropical and subtropical regions of influenza transmission have all year, but are also subject to oscillations, influenced by rainy seasons. In these regions may occur over a period of viral activity a year.

Cerbino used data from the Information System for Notifiable Diseases (Sinan) from the Ministry of Health to analyze the number of deaths among confirmed cases of influenza in the years 2009 and 2010. Between April 19, 2009 and January 2, 2010, were 23.3 reported cases per 100,000 inhabitants. In the same period 2051 influenza deaths occurred, leading to a mortality rate of 1.1 per 100,000 inhabitants. In the southern region, the rate was 3.0 deaths per 100 thousand inhabitants, while in the Northeast was 0.1 deaths per 100 thousand inhabitants. The north, northeast and center-west contributed only 6% of the total cases.

<b> and Oseltamivir tamiflu </ b>

The thesis also shows that the drug oseltamivir, commercially known as Tamiflu, is effective in preventing deaths from influenza A. The tamiflu, recommended by the Ministry of Health and the World Health Organization (WHO) for suspected H1N1, was held in 2009 on 426 patients admitted to hospitals in Rio de Janeiro and reduced by 60% the risk of death. Reduction was observed in patients taking oseltamivir up to four days of symptom onset (Follow the box below the most frequent symptoms). The thesis shows that the drug is effective even after 48 hours of symptom onset, underscores Cerbino. The Tamiflu is sold in pharmacies and distributed by Unified Health System (SUS). You do not need a prescription to buy the drug.

<b> Adverse Reactions </ b>

The third search result concludes that vaccines with adjuvants - manufactured with the virus and lipid compounds that increase the effect of the individual's immune response - used in the first campaign against H1N1, have up to six times greater risk of causing adverse reactions such as pain , redness and swelling. It is important to take into account the factors influencing adherence to vaccination, and one of the determinants are the adverse reactions, the researcher recalls.

   Palavras-chave:   H1N1    Influenza    Swine flu    Fiocruz    Fundação Oswaldo Cruz    Calendar   
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