Science and Technology
publicado em 30/07/2012 às 15h19:00
   Dê o seu voto:

Solving the mystery of how cigarette smoking weakens bones

Cigarette smoke makes people produce excessive amounts of two proteins that trigger a natural body process that breaks down bone

 
font size
A-
A+

Almost 20 years after scientists first identified cigarette smoking as a risk factor for osteoporosis and bone fractures, a new study is shedding light on exactly how cigarette smoke weakens bones. The report, in ACS' Journal of Proteome Research, concludes that cigarette smoke makes people produce excessive amounts of two proteins that trigger a natural body process that breaks down bone.

Gary Guishan Xiao, from Creighton University and colleagues point out that previous studies suggested toxins in cigarette smoke weakened bones by affecting the activity of osteoblasts, cells which build new bone, and osteoclasts, which resorb, or break down, old bone. Weakening of the bones, known as osteoporosis, can increase the risk of fractures and is a major cause of disability among older people. To shed light on how cigarette smoking weakens bones, the scientists analyzed differences in genetic activity in bone marrow cells of smokers and non-smokers.

They discovered that human smokers produce unusually large amounts of two proteins that foster production of bone-resorbing osteoclasts compared to non-smokers. Experiments with laboratory mice confirmed the finding.

Source: Isaude.net
   Palavras-chave:   Bones    Weakens bones    Osteoporosis    Cigarette    Smoking    Cigarette smoking   
  • Share this pageShare this page
  • Share this pageCorrect
  • ShareShare
  • AlertAlert
Reduced link: 
  • You are recommending this story: Solving the mystery of how cigarette smoking weakens bones
  • Fill in the following form to send your recommendation to your friend:

  • You are suggesting a correction for this story: Solving the mystery of how cigarette smoking weakens bones


Receba notícias do iSaúde no seu e-mail de acordo com os assuntos de seu interesse.
Seu nome:
Seu email:
Desejo receber um alerta com estes assuntos:
bones    weakens bones    osteoporosis    cigarette    smoking    cigarette smoking   
Comments:
Comment
Leave your comment
Close
(Required fields are marked with an *)

(Your email address will never be published or shared.)

Enter the letters and numbers below and click in the button "send"

  • Twitter iSaúde
advertising
Informe Saúde printed version

Recommend the portal
Close [X]
  • You are recommending this story: http://www.isaude.net
  • Fill in the following form to send your recommendation to your friend:

RSS news from the portal  iSaúde.net
Get the newsletter of the portal  iSaúde.net
Recommend the portal iSaúde.net
News from  iSaúde.net in your blog or website.
Get news on the subject of your interest.
© 2000-2011 www.isaude.net Todos os direitos reservados.