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publicado em 07/05/2012 às 13h35:00
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In tests on animals and humans, the formulation has proven effective in combating wrinkles without the risk of skin irritation

 
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A survey of the Faculty of Pharmaceutical Sciences (FCF) of UNESP Araraquara developed a formulation based on nanotechnology to combat skin aging. In tests on animals and humans, the formulation has proven effective in combating wrinkles without the risk of skin irritation.

The formulation contains liquid crystals made from silicon with droplets on the order of nanometers, which are able to penetrate the inner layers of the epidermis and control the speed at which the active ingredient is released, he explains FHR Marlus Chorilli, who developed nanotechnological system for his doctorate, held at the Campus of Araraquara, under the guidance of Professor Maria Virginia Scarpa.

Nanotechnology works on a scale corresponding to 1 millimeter divided 1 million times. The system created in Unesp contains silicon nanostructures to carry more of the substances used in anti-aging creams on the market, retinyl palmitate. According Chorilli the nanossistema can improve the stability and effectiveness of retinol, a substance which is sensitive to environmental degradation.

<b> test in humans </ b>

In tests on rabbits, the professor found that the formulation did not cause skin irritation. Furthermore, the formulation increased the number of fibroblasts - cells able to produce more collagen and elastic fibers, the major responsible for providing strength and tone of skin.

Then Chorilli evaluated the efficacy of the formulation on the skin of 32 women aged between 30 and 45 years. The volunteers applied daily formulation in the area around one eye (the region of the other eye has not received any product) for 30 days. After this period, the teacher found a significant decrease in the size and depth of wrinkles in the area with the formulation, compared to the region that has received the cosmetic product.

"The results suggest that the product can be a great ally in the fight against wrinkles, which are increasingly common, even in younger people," says Chorilli.

Source: UNESP
   Palavras-chave:   Nanocosmético    Nanotechnology    UNESP    Wrinkle    Dermatology    Skin   
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