publicado em 24/01/2012 às 07h30:00
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Read books and do puzzles reduces protein associated with Alzheimer's

Study identifies biological factor that takes mental activities act as a way to avoid the neurological condition

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People that keep the brain active throughout life with cognitively stimulating activities like reading, writing and games have lower levels of beta amyloid protein linked to Alzheimer's disease, suggests a study published in the digital edition of the journal "Archives of Neurology."

The protein in question form senile plaques in the brains of Alzheimer patients to concentrate and affect transmission between nerve cells in the brain.

Although previous studies have suggested that they perform mental activities helps prevent Alzheimer's in adulthood, this new research identifies the biological factor, which may help develop new strategies for treatment.

"More than simply providing resistance to Alzheimer's disease, activities to stimulate the brain can affect a primary pathological process of the disease," said one of the principals involved in the study, William Jagust, professor of neuroscience at the University of California.

This would indicate that the cognitive treatment "may have an important effect 'modifier' of the disease if applied to the benefits of treatment with sufficient advance, before symptoms appear," he said.

Alzheimer's is a neurodegenerative disease that mainly affects older adults. Its main symptom is memory loss that leads to dementia.

The researchers asked 65 healthy adults, and cognitively normal older than 60 years, to indicate the frequency with which participated in mental activities like reading books and newspapers and writing letters or emails.

The questions were focused on various points of life from six years to the present.

Participants made extensive neuropsychological tests to assess their memory and other cognitive functions, and have undergone an examination and brain scanners developed at Berkeley Lab to see the beta amyloid protein.

The researchers compared the results with those of healthy subjects 10 patients diagnosed with Alzheimer's disease and 11 healthy persons of 20 years, finding a significant association between higher levels of cognitive activity throughout life and low levels of protein.

"This is the first time the level of cognitive activity is related to the accumulation of beta amyloid in the brain," said Susan Landau, a researcher at the Helen Wills Neuroscience Institute and the Laboratory of Berkeley (California).

"The accumulation of these proteins probably starts many years before symptoms appear. The beginning of the intervention can be much earlier, and that is why we are trying to identify the lifestyle factors may be related to the first change," said Susan

Source: EFE
   Palavras-chave:   Brain    Brain active    Reading    Writing    Games    Alzheimer's    Alzheimer's disease   
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