publicado em 26/11/2011 às 10h00:00
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Method of interpretation of radiographs improves diagnosis of breast cancer

System was built based on the information spread by breast radiation when exposed to x-rays

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Patient is subjected to X-ray examination
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Patient is subjected to X-ray examination

Method developed at the Faculty of Philosophy, Sciences and Letters of Ribeirão Preto (FFCLRP) proposes a new way to identify breast cancer. The system developed by physician André Luiz Coelho Conception was built based on information from scattered radiation for breast cancer when exposed to X-ray examinations Previously these data were considered undesirable because it reduces the image quality compared to mammography.

During the research, Luiz André developed the combination of the two treatment techniques: observation of tissue from the scattering of X-ray mammography and tradition.

We analyzed normal tissues, malignant and benign, to develop a model based on differences in the compositions of the breast tissue in order to diagnose cancer based on structural information of the samples.

<b> Unexpected Behavior </ b>

Over the age, the fibers of the breast tend to be replaced by fat cells, making the breasts sag. Thus, the younger the breast tissue is more fibrous.

The fibers are made mostly of water. Since fat is primarily composed of fatty acids. This condition was responsible for the different results in scattering of X-rays in the medium angle. However, it only occurred as expected in normal tissues. Fabrics with malignant and benign tumors showed different behaviors.

The breast tumors started to have more water, the reverse of that considered as the natural tendency is to lose water and gain fatty acids over time. The hypothesis is that the tumor needs an increased vascularity of the breast to develop, it also means increasing the percentage of molecules of water points.

The researcher explains that innovation is the study of a combination of scattering techniques at low and medium angle and interpretation of data, which were used to create a model for diagnosing tissue samples of normal breast, benign or malignant.

In the region of low angle, the differences are given with respect to the collagen fibers. In malignant samples, these fibers showed a difference when compared with normal samples: they were much less frequent, with greater variation in the frequency of the structure (looser). According to André Luiz, one possible explanation is that the invasion of cancer in the space causes the breakdown of collagen fibers.

To repair such damage, the body tries to rebuild that connection. The reconstruction of a connection is never as perfect as the original. This is visible in the scattering of the rays, which occur at a low angle. It is this imperfect rebuilding that can be identified in the scattering of the rays.

To learn more about the method created by André Luiz Coelho Conceição, read the complete article aqui.

Source: USP
   Palavras-chave:   Cancer    Radiology    Diagnostic imaging    USP    Universidade de São Paulo    Radiation    X-Ray   
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Cancer    radiology    diagnostic imaging    USP    Universidade de São Paulo    radiation    X-Ray   
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