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publicado em 05/10/2011 às 20h39:00
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Complications of chronic kidney disease occur earlier in childhood

The largest prospective study of children with chronic kidney disease confirmed that complications occur early

 
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About this fact that can lead to a change in treatment, the largest prospective study of children with chronic kidney disease has confirmed the suspicions of some experts that complications occur early. The findings suggest the need for earlier and more aggressive monitoring of blood pressure, anemia and other problems associated with kidney disease, according to the specialist in pediatric nephrology Marva Moxey-Mims.

The growth failure, metabolic abnormalities and risk factors of cardiovascular disease such as hypertension, occur even in a glomerular filtration rate of 50 mm per second in children with chronic kidney disease. The glomerular filtration rate is a measure of kidney function and a rate of 50 mm per minute is approximately half of normal. Despite therapy, the prevalence of these complications increases from two to four times the fall rate.

Moxey-Mims noted that many experts previously thought that the complications of renal disease such as anemia, acidosis, acidosis and elevated phosphate, usually did not happen until the kidney function worse than stay at a rate of 50 mm per minute .

Metabolic abnormalities and risk factors for cardiovascular disease have rarely been systematically studied in children with chronic kidney disease. We seek to identify the point along the spectrum of glomerular filtration rate in which several common consequences of chronic kidney disease becomes more prevalent, said Dr. Susan Furth.

Considering that many children may not be diagnosed with kidney disease until they are at the lowest level of kidney function, this is important. Even more than a glomerular filtration rate of 50 mm per minute, some of the abnormalities are already there. Actually, they get worse when the kidney function drops, but the study shows that problems begin to develop earlier than many thought. Now we know that children who are with a glomerular filtration rate of 50 millimeters per minute are the ones that should be looked at more closely, Moxey-Mims said.

Source: Isaude.net
   Palavras-chave:   Nephrology    Children    Chronic kidney disease    Pessão pressure    Anemia   
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