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publicado em 07/09/2011 às 12h30:00
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Cells that stimulate hair growth in mice can reverse baldness

Scientists want to replicate in human hair follicles the same signals that instruct cells of these mice to produce the

 
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Researchers from Yale University in the United States, identified the skin cells are rich in fats responsible for stimulating hair growth in mice. The discovery could be used to reverse the balding process in humans.

The study, published in the journal Cell, shows that these molecular signals derived from skin cells were necessary for the growth of the animals tested. "If we can get these cells to talk to those dormant at the base of hair follicles, we might be able to make hair grow back," said senior study author, Valerie Horsley.

Men with pattern baldness still have stem cells in the follicle roots, but they lose the ability to initiate regeneration of hair. Scientists know that they need signals from within the skin to stimulate growth, but the source of these signals was not known.

Horsley's team observed that when the hair dies, the layer of fat on the scalp shrinking the thickness of the skin. When hair growth begins, this layer expands in a process called adipogenesis. The researchers found that a type of stem cell, involved in the creation of new fat cells, it was necessary for the regeneration of the mice. They also found that they produce these molecules called PDGF (platelet growth factors derived), which are needed to stimulate the hairline.

The team now is trying to identify other precursors of signals produced by fat cells that may play a role in regulating hair growth. They also plan to find out if the same chemical processes occur in humans.

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Source: Isaude.net
   Palavras-chave:   Baldness    Hair    Skin cells    Fat    Hair    Yale University    Valerie Horsley   
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