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publicado em 26/08/2011 às 16h00:00
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Low levels of brain hormone are associated with serious suicidal behavior

Discovery could lead to a better understanding and new treatments for people who attempt suicide

 
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Researchers at Karolinska Institutet in Sweden found that low levels of the hormone oxytocin in the brain are associated with a more serious suicidal behavior. The results showed that people who attempted suicide with greater intent to die had lower hormone levels. The discovery could lead to a better understanding and new treatments for those who attempt suicide.

Oxytocin is a neuropeptide that is secreted in the body during childbirth and breastfeeding to induce a calming effect and analgesic. Animal studies have also shown that oxytocin promotes social interaction and attenuates the activation of the stress system. In the new study, researchers showed that low levels of cerebrospinal fluid (CSF) and oxytocin in blood plasma were associated with serious and thoughtful attempts suicide with a stronger intent to die.

Twenty-eight persons who attempted suicide and 19 healthy volunteers participated in the study. The idea of ​​suicide was measured on two levels. People who attempted suicide tended to decrease the levels of oxytocin in the CSF compared with healthy volunteers. Individuals with the most serious attempts and had planned to lower levels of oxytocin in CSF and plasma. The association was stronger in men than in women.

There was a strong correlation between hormone levels low and high level of planning with little chance of being discovered or being interrupted while attempting suicide. The intranasally administered oxytocin can reduce anxiety and improve social contact for people with certain types of psychiatric disorder. According to what we know so far, no study has assessed this type of treatment individuals who attempted suicide. We see this as an opportunity for new forms of treatment, "said lead researcher in the Department of Clinical Neurosciences, Jussi Jokinen.

The artigo na íntegra (in English) can be purchased on the website of ScienceDirect.

Source: Isaude.net
   Palavras-chave:   Oxytocin    A hormone    Suicide    Cerebrospinal fluid    Plasma   
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