Science and Technology
publicado em 01/08/2011 às 12h00:00
   Dê o seu voto:

Adrenaline has a prominent place to reverse cardiac arrest

Study of more than 600 victims provided the best evidence in favor of substance use to restore circulation

 
font size
A-
A+

Some pieces of information on this page may have been automatically translated. Makernews is not responsible for the irregularities resulting from these translations. When in doubt,      consult the original text.



Adrenaline has maintained a prominent place in the guidelines for the treatment of cardiac arrest, despite limited evidence for or against use. The research versus Adrenaline versus Placebo Cardiac Arrest (PACA), by Professor Ian G. Jacobs and colleagues provides the best evidence yet exists to support the use of adrenaline in the treatment of cardiac arrest.

In this double-blind unicenter, 601 victims of cardiac arrest outside the hospital were randomized to receive placebo (sodium chloride 0.9%) or adrenaline during treatment. Data available from 534 patients (262 placebo and 272 with epinephrine) showed no difference in the end point of the first analysis of the study (survival to hospital discharge), but showed that spontaneous circulation was restored three times with adrenaline ( 23.5%) than with saline placebo (8.4%).

According to Professor Jacobs' Our present study highlights the challenges in conducting randomized clinical trials on cardiac arrest, particularly when they involve therapies accepted but unproven. Although we have not succeeded in demonstrating that adrenaline improved chance of survival to hospital discharge , showed that it increased the likelihood of restoring the circulation after cardiac arrest. "

Source: Isaude.net
   Palavras-chave:   Adrenaline    Cardiac arrest    Blood circulation    Hospital discharge    Placebo   
  • Share this pageShare this page
  • Share this pageCorrect
  • ShareShare
  • AlertAlert
Reduced link: 
  • You are recommending this story: Adrenaline has a prominent place to reverse cardiac arrest
  • Fill in the following form to send your recommendation to your friend:

  • You are suggesting a correction for this story: Adrenaline has a prominent place to reverse cardiac arrest


Receba notícias do iSaúde no seu e-mail de acordo com os assuntos de seu interesse.
Seu nome:
Seu email:
Desejo receber um alerta com estes assuntos:
Adrenaline    cardiac arrest    blood circulation    hospital discharge    placebo   
Comments:
Comment
Leave your comment
Close
(Required fields are marked with an *)

(Your email address will never be published or shared.)

Enter the letters and numbers below and click in the button "send"

  • Twitter iSaúde
advertising
Informe Saúde printed version

Recommend the portal
Close [X]
  • You are recommending this story: http://www.isaude.net
  • Fill in the following form to send your recommendation to your friend:

RSS news from the portal  iSaúde.net
Get the newsletter of the portal  iSaúde.net
Recommend the portal iSaúde.net
News from  iSaúde.net in your blog or website.
Get news on the subject of your interest.
© 2000-2011 www.isaude.net Todos os direitos reservados.