Science and Technology
publicado em 22/06/2011 às 03h00:00
   Dê o seu voto:

Blueberries help lab mice to produce strong bones

Studies suggest that polyphenols responsible for the color of blueberries can help in building strong bones

font size

Some pieces of information on this page may have been automatically translated. Makernews is not responsible for the irregularities resulting from these translations. When in doubt,      consult the original text.

Compounds found in blueberries may have a powerful effect on the formation of strong bones and healthy, the results of studies in mice hold true in humans.

Jin-Ran Chen is a professor in the department of pediatrics and specializes in research on how our diet during childhood and early adulthood affects growth and development of bones and the risk of developing osteoporosis or other bone degenerative diseases in later years.

Chen studies in mice young and fast growing suggest that polyphenols, compounds that give blueberries their blue color, purple and red, can assist in building strong bones. The work paved the way for further research can reveal whether that blueberries could be used in future treatments to boost the development of bone mass and help prevent osteoporosis.

The survey found that rats fed diets containing 10% freeze-dried blueberry powder had significantly more bone than those fed diets containing no dust.

When the researchers exposed lab cultures of bone-forming cells (osteoblasts) to the blood (fluid) of the animals, they found that the fluid blood of rats fed blueberry was associated with an increase in the development of osteoblasts in bone cells mature and functional.

The fluid blood in the rats fed blueberry had elevated levels of phenolic acids derived from the polyphenols responsible for the coloration of the fruit. Research suggests that phenolic acids may have influenced the construction of bones in rats. Studies are needed to determine whether these benefits occur in humans, Chen said.

Chen's research also suggests that the phenolic acids stimulated the bone-building through a pathway that may involve, for example, a protein, beta-catenin (which takes the osteoblasts to become mature and functional) and two genes, TCF and LEF (responsible for promoting the synthesis of beta-catenin).


  • Share this pageShare this page
  • Share this pageCorrect
  • ShareShare
  • AlertAlert
Reduced link: 
  • You are recommending this story: Blueberries help lab mice to produce strong bones
  • Fill in the following form to send your recommendation to your friend:

  • You are suggesting a correction for this story: Blueberries help lab mice to produce strong bones

Receba notícias do iSaúde no seu e-mail de acordo com os assuntos de seu interesse.
Seu nome:
Seu email:
Desejo receber um alerta com estes assuntos:
blueberry    builds strong bones    strong bones    osteoporosis    polyphenols    freeze-dried blueberry powder    phenolic acids    osteoblasts   
Leave your comment
(Required fields are marked with an *)

(Your email address will never be published or shared.)

Enter the letters and numbers below and click in the button "send"

  • Twitter iSaúde
Informe Saúde printed version

Recommend the portal
Close [X]
  • You are recommending this story:
  • Fill in the following form to send your recommendation to your friend:

RSS news from the portal  iSaú
Get the newsletter of the portal  iSaú
Recommend the portal iSaú
News from  iSaú in your blog or website.
Get news on the subject of your interest.
© 2000-2011 Todos os direitos reservados.