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publicado em 10/06/2011 às 03h00:00
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Sleep apnea increases the incidence of complications during pregnancy

Study shows that women with severe apnea had a higher prevalence of gestational diabetes and preterm delivery

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Sleep apnea is associated with an increased risk of pregnancy complications. It suggests that the study by researchers at Northwestern University, USA.

Results show that women with severe sleep apnea showed the highest incidence of adverse pregnancy outcomes. This increased prevalence was mainly responsible for the higher incidence of gestational diabetes and preterm premature.

The authors found that sleep apnea has been associated with heart disease, metabolic syndrome and mortality in non-pregnant. However, few studies have examined the relationship between sleep apnea in pregnancy and obstetric outcome.

"Our findings suggest that sleep disordered breathing in moderate to severe may be associated with adverse pregnancy outcomes, particularly gestational diabetes and preterm birth," said lead investigator, Francesca L. Facco. "However, it is unclear whether sleep-disordered breathing is a risk factor for adverse pregnancy outcomes independent of obesity."

According to the American Academy of Sleep Medicine, sleep apnea is a form of sleep-disordered breathing, which involves the partial reduction (hypopnea) and pauses (apneas) in breathing during sleep. The most common form of sleep apnea is obstructive sleep apnea, which occurs when muscles relax during sleep, causing soft tissue in the back of the throat to close and lock the upper airway. The pauses in breathing that result can produce sharp reductions in oxygen saturation in the blood and reduce blood flow to the brain. Most people with the condition snore loudly and frequently, and they often experience excessive daytime sleepiness.

Women with an apnea-hypopnea index from 14.9 to five respiratory pauses per hour of sleep were considered as having sleep apnea from mild to moderate, and those with an index of 15 or more were classified as having severe sleep apnea .

The analysis examined the association between sleep apnea and three adverse pregnancy outcomes: pregnancy-induced hypertension, gestational diabetes and early preterm birth at 34 weeks or less.

Facco added that more research is needed to clarify how sleep apnea and obesity interact with maternal and neonatal health.

"More studies, especially large prospective studies using objective measures of sleep-disordered breathing, are needed to confirm this relationship and analyze the interaction between sleep-disordered breathing and body mass index," said Facco. "If the relationship is confirmed, further studies are needed to evaluate the role of treatment of sleep disordered breathing in pregnancy."


   Palavras-chave:   Sleep apnea    Gestational diabetes    Premature birth    Northwestern University   
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