Science and Technology
publicado em 03/03/2011 às 03h00:00
   Dê o seu voto:

Mouse model sheds light on damage to human nerve cells in IDAs

"Previously, the rhesus monkey was the only animal model for studying the early stages of HIV infection"

 
font size
A-
A+

Some pieces of information on this page may have been automatically translated. Makernews is not responsible for the irregularities resulting from these translations. When in doubt,      consult the original text.



New mouse model similar to how the body responds to the initial infection of AIDS sheds light on the damage the disease causes nerve cells.

Approach, developed by researchers at the National Institutes of Health, the United States show that HIV infection in the nervous system leads to inflammatory responses, changes in brain cells and damage to neurons.

This is the first study to show that neuronal loss during the early stages of HIV infection in a mouse model.

"This finding of the research should help us learn more about how HIV affects the brain works in its initial phase, which could lead to better treatments that can be used early in the disease," said researcher Nora D. Volkow.

"The study is the culmination of 20 years to develop a model of rats with early neurological complications of HIV infection in humans," said one of the study's authors, Howard Gendelman. "Previously, the rhesus monkey was the only animal model for studying the early stages of HIV infection. However, its use was limited due to problems with the expense and generalize the results across species. Relevant rodent models that mimic human disease have been sorely needed. "

Source: Isaude.net
   Palavras-chave:   AIDS    HIV    Rat model    Nerve cells    National Institutes of Health   
  • Share this pageShare this page
  • Share this pageCorrect
  • ShareShare
  • AlertAlert
Reduced link: 
  • You are recommending this story: Mouse model sheds light on damage to human nerve cells in IDAs
  • Fill in the following form to send your recommendation to your friend:

  • You are suggesting a correction for this story: Mouse model sheds light on damage to human nerve cells in IDAs


Receba notícias do iSaúde no seu e-mail de acordo com os assuntos de seu interesse.
Seu nome:
Seu email:
Desejo receber um alerta com estes assuntos:
AIDS    HIV    rat model    nerve cells    National Institutes of Health   
Comments:
Comment
Leave your comment
Close
(Required fields are marked with an *)

(Your email address will never be published or shared.)

Enter the letters and numbers below and click in the button "send"

  • Twitter iSaúde
advertising
Informe Saúde printed version

Recommend the portal
Close [X]
  • You are recommending this story: http://www.isaude.net
  • Fill in the following form to send your recommendation to your friend:

RSS news from the portal  iSaúde.net
Get the newsletter of the portal  iSaúde.net
Recommend the portal iSaúde.net
News from  iSaúde.net in your blog or website.
Get news on the subject of your interest.
© 2000-2011 www.isaude.net Todos os direitos reservados.