Science and Technology
publicado em 22/02/2011 às 15h00:00
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Printer tissues and organs can mean historical change in medicine

Scientists use a conventional printer, replacing the ink by a mobile solution to produce organs in 3D

 
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Foto: Reprodução Medical University of South Carolina
Beginning the process of making new printer ink. Living cells are spun in a centrifuge, cut and crushed and this results in tiny spheres that flow like a liquid
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Beginning the process of making new printer ink. Living cells are spun in a centrifuge, cut and crushed and this results in tiny spheres that flow like a liquid

Technology used to print documents can also create living tissues. The technique, developed by scientists at the Medical University of South Carolina and Clemson University (USA), may in the near future, be used to produce miniature organs for testing drugs. In matters disclosed by BBC News, the scientists behind the project said they still hope to one day be able to use printing technology to create whole organs.

conventional printing technology

When a document is printed, the ink is distributed in a specific pattern on paper. To create three dimensional tissue structures, American researchers modificaram impressoras para usar uma solução de célula em vez de tinta.

They then repeatedly printed layers, creating a 3D structure. Experts in Britain said that the use of cells instead of a polymer represents a breakthrough for regenerative medicine. However, the use of technology in medical treatment still has a long way, they warned.

wwwAAASorg
This emerging technology was demonstrated at a news briefing Sunday at the AAAS Annual Meeting. During the presentation, the machine constructed a model of ear cartilage printed out of silicon.

The technique

In the technique, developed by doctors in South Carolina and Clemson, conventional ink cartridges were washed and refilled with cellular solutions.

Then, the software that controls how fluids behave cartridges, including properties such as resistance and temperature, has been rescheduled.

To create 3D structures, a non-toxic, biodegradable gel designed by scientists at the University of Washington. The gel is liquid below 20 ° C and solidifies above 32 ° C.

During the research, scientists found that while the layers were thin enough for the clumps come into contact with each other, the fabric pieces would fuse.

The gel can be easily removed, leaving the 3D structure.

The research team, led by Dr. Vladimir Mironov, Medical University of South Carolina, said the printing technique of tissue allowed tissue to be created faster than existing techniques, where a scaffolding is done, and cells are seeded on it.

"The problem is that you can never create an organ with a blood supply," the researcher told the BBC.

"We can print fabric that is two inches thick in two hours, and can print a system of blood vessels."

"The next step is to print a small element of an organ, called a functional structural unit. It should contain all the necessary elements that reflect organ function."

Mironov added that "these organs could be used as test systems for testing drugs or treatment that is best for a patient. For example, a biopsy of a tumor might be taken and tested drugs to see which is best suited for the patient. "

whole organs

Anthony Atala, tissue engineer at Harvard University, "this technology is extremely exciting because it has the potential to overcome some major obstacles that we saw in the past."

But Professor Tim Hardingham, director of the Center for Tissue Engineering in the UK told the BBC that "printing technology represents a variety of promises."

"But there is much work to learn how we can actually apply it."

Source: Isaude.net
   Palavras-chave:   3D printers    Tissues    Mini organ regeneration   
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