Science and Technology
publicado em 28/10/2010 às 15h00:00
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Minimally invasive glucose testing eliminates bites to check glucose levels

The new technique may offer a more detailed picture of blood glucose concentrations in diabetic patients

 
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A group of researchers at the University of Tokyo, Japan, developed a minimally invasive glucose testing. The new technique makes the traditional finger prick thing of the past for those who suffer from diabetes. The test can also provide a more detailed picture of glucose concentrations that vary throughout the day.

Shoji Takeuchi and his colleagues, working with collaborators in industry and at Kyoto University Hospital, have developed a fluorescent bead that can be injected into the skin. The granules contain a type of boronic acid that binds to glucose molecules. Once inside the blood, these accounts, sensitive, can be traced to reveal the levels of blood sugar through skin exposure to light.

In practice, diabetic patients need devices that contain a source of excitation light and photodiode to read the fluorescent signal. "The device would be as small as a watch or a piercing and diabetic patients could carry the device," said Takeuchi.

In vitro tests, the researchers observed an increase in relative fluorescence due to increased concentrations of glucose. They also tested in vivo by injecting fluorescent beads in her ear skin of a mouse, using a common needle in clinical settings.

Takeuchi believes the technique could be commercialized within five years, but there are still aspects of science that need to be developed before it can be taken to a clinical trial. "The next step is to improve the computer so they have a little protein adsorption - this is important to maintain a stable micro-body," he explains.

The work of Takeuchi and his colleagues described in a recent article in the journal Proceedings of the National Academy of Sciences.

Germany

Source: Isaude.net
   Palavras-chave:   Diabetes    Blood glucose test    Fluorescent light    Beads    Glucose   
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