Science and Technology
publicado em 03/06/2009 às 20h00:00
   Dê o seu voto:

Chinese create stem cells from pigs

The discovery opens the way to abandon the use of human embryos in the race to produce organs for transplants.

font size

Some pieces of information on this page may have been automatically translated. Makernews is not responsible for the irregularities resulting from these translations. When in doubt,      consult the original text.

Foto Divulgação / IdMed
Cells taken from the ear of pigs were transformed into stem cells
  « Previous
next »  
Cells taken from the ear of pigs were transformed into stem cells

A group of Chinese scientists succeeded in obtaining pluripotent stem cells - capable of developing into any kind of tissue - the cells from pigs. It is the first time such a feat is achieved from somatic cells of hoofed animals (known as ungulates).

The research was published in the Journal of Molecular Cell Biology, a new journal from Oxford Press. According to the publishers, the implications are important, since the study may lead to the creation of models for human genetic diseases and animal organs suitable for transplantation into humans, animals and the development of disease resistant.

Law Xiao, coordinator of the stem cell laboratory of the Institute of Biochemistry and Cell Biology Shanghai, and colleagues induced pluripotent cells from the use of transcription factors in order to reprogram cells taken from the ear and the spinal cord of pigs.

After the chemical cocktail of factors to reprogram cells was introduced by a virus, the cells developed in laboratory colonies of stem cells similar to embryonic cells. Tests have confirmed that they were able to differentiate into cell types that make up the three germ layers - endoderm, mesoderm and ectoderm - a quality of all embryonic stem cells.

With the information obtained from the successful induction of pluripotent cells will make it easier for researchers to develop embryonic stem cells from embryos of pigs or other ungulates.

Pluripotent stem cells from pigs will be very useful in several ways, such as genetically modified produce copies for use in organ transplants for humans. The species of pigs are pretty similar to the man in form and function, as the dimensions of the bodies, said Xiao.

We can use embryonic stem cells or induce stem cells to modify genes of the immune system of pigs in order to make the body of the animal is compatible with the human immune system. With this, we would use the pigs as donors to provide organs for patients who do not submit rejection, he noted.


Source: FAPESP
  • Share this pageShare this page
  • Share this pageCorrect
  • ShareShare
  • AlertAlert
Reduced link: 
  • You are recommending this story: Chinese create stem cells from pigs
  • Fill in the following form to send your recommendation to your friend:

  • You are suggesting a correction for this story: Chinese create stem cells from pigs

Receba notícias do iSaúde no seu e-mail de acordo com os assuntos de seu interesse.
Seu nome:
Seu email:
Desejo receber um alerta com estes assuntos:
stem cell    pig cloning    Chinese Institute of Biochemistry and Cell Biology Shanghai    Lei Xiao   
Leave your comment
(Required fields are marked with an *)

(Your email address will never be published or shared.)

Enter the letters and numbers below and click in the button "send"

  • Twitter iSaúde
Informe Saúde printed version

Recommend the portal
Close [X]
  • You are recommending this story:
  • Fill in the following form to send your recommendation to your friend:

RSS news from the portal  iSaú
Get the newsletter of the portal  iSaú
Recommend the portal iSaú
News from  iSaú in your blog or website.
Get news on the subject of your interest.
© 2000-2011 Todos os direitos reservados.